The McMaster Centre for Pre-Clinical and Translational Imaging (MCPTI) is a facility that specializes in functional and structural imaging of small animals and is available to all researchers. The facility consists of a Philips Mosaic PET and Gamma Medica X-SPECT (SPECT/CT), two of the most accurate clinical imaging modalities.
Preclinical imaging is non-invasive and longitudinal studies can be performed to characterize disease progression and drug efficacy in the same animal. It can also provide information on biological processes in living tissues that can be visualized and quantified. Fusion of functional images (eg. from PET, SPECT) with anatomical images (CT) helps to determine relationships between functional and structural changes.